The obvious clinical resemblance between certain aspects of the amyostatic syndrome of epidemic encephalitis and certain manifestations in schizophrenia, particularly of the so termed catatonic order, has been remarked by numerous observers (Bostroem,1 Deny and Klippel2 and others). This raises in a general way the question of the possibility of the occurrence, in some respects, in both disorders, of a somewhat similar pathology. Furthermore, it has been actually determined through study along more or less strictly histopathologic lines that in schizophrenia, among other attributes, there does seem to obtain a pathology of like locale to that in epidemic encephalitis. In this connection reference is made especially to the work of Laignel-Lavastine,3 Marcuse,4 Füngeld,5 Reichardt,6 Josephy,7 Buscaino8 and Freeman.9 Jelliffe's10 comment in this connection is especially interesting:
No analysis of the dementia praecox situation is availing which leaves out of consideration