Serum C-reactive Protein (CRP)

Serum C-reactive Protein  (CRP)

Site: Hip and Knee

Statistics

Sensitivity: 0,88

Specificity: 0,87

Cutoff: The one in use in your lab

Patients: 3909 - 30 studies

General Information

Description

CRP is produced by the liver as an acute-phase reactant, and elevated levels are seen in the case of systemic infection and in peri-prosthetic joint infections. Various inflammatory conditions are also known to increase C-RP levels.

References

Berbari E, Mabry T, Tsaras G, Spangehl M, Erwin PJ, Murad MH, Steckelberg J Osmon D. Inflammatory blood laboratory levels as markers of prosthetic joint infection: a systematic review and meta-analysis.  J Bone Joint Surg Am 2010 Sep 1;92(11):2102-9.